Estudio de la susceptibilidad a vancomicina de cepas de Staphyloccus spp., aisladas del hospital Antonio Patricio de Alcalá, Cumaná, estado Sucre | Vancomycin susceptibility study of Staphylococcus spp. Strains isolated from Antonio Patricio de Alcalá hospital, Cumaná, Sucre state

Lorena Abadia-Patiño; Sarai Acuña; Isangel Manosalva

Estudio de la susceptibilidad a vancomicina de cepas de Staphyloccus spp., aisladas del hospital Antonio Patricio de Alcalá, Cumaná, estado Sucre | Vancomycin susceptibility study of Staphylococcus spp. Strains isolated from Antonio Patricio de Alcalá hospital, Cumaná, Sucre state

Lorena Abadia-Patiño, Sarai Acuña, Isangel Manosalva

Resumen

De todas las cepas de Staphylocccus aureus almacenadas en el cepario del Laboratorio de Resistencia Bacteriana del IIBCAUDO, se analizaron 14 para determinar la disminución de susceptibilidad a vancomicina. Sesenta y cuatro por ciento de las cepas crecieron en el cribado de vancomicina. La CMI a vancomicina de las cepas estuvo entre 1 y 2 mg/L por microdilución. La CMI por dilución en agar fue entre 2 y 4 mg/L. La CMB de las cepas fue de 2 y 4 mg/L. Ninguna cepa fue tolerante. No se detectaron cepas hVISA por PAP-AUC. Se recomienda realizar el cribado de vancomicina en cepas aisladas de sitios estériles.

Palabras clave: Glicopéptidos, bacteriemias, endocarditis, VISA.

Abstract

From all strains of Staphylocccus aureus stored in the Bacterial Resistance Laboratory ceparium of IIBCAUDO, fourteen strains were analyzed to determine the decreasing susceptibility to vancomycin. Sixty four percent of strains grew on vancomycin screening. MIC vancomycins were between 1 and 2 mg/L by microdilution method. MIC agar dilutions were 2 and 4 mg/L. MBC were 2 and 4 mg/L. None of the strain was tolerant. No hVISA strains with PAP-AUC method was detected. We suggest vancomycin screening for all strains isolated from sterile sites.

Key words: Glycopeptides, bacterimias, endocarditis, VISA.

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